Pomalidomide-PEG4-C2-NH2 (hydrochloride)

• UNSPSC Description:

  Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs..

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pomalidomide-peg4-c2-nh2-hydrochloride.html

• Purity:

  97.01

• Solubility:

  DMSO : 220 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.Cl

• Molecular Weight:

  528.98

• References & Citations:

  [1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2357105-92-9