ST-IN-1

CAT: 0804-HY-169084Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-169084Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ST-IN-1 (compound (R) -1) is a selective ST inhibitor (Ki=70 nM, rat a-2,6-ST; Ki=19 nM, hST6GAL1) with antitumor activity. ST-IN-1 inhibits tumor growth and metastasis by delipidating the surface of tumor cells[1].

UNSPSC

12352005

Target

Glycosyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/st-in-1.html

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(OC(P(O)(O)=O)C3=CC=CC(OC4=CC=CC=C4)=C3)=O

Molecular Formula

C22H24N2O13P2

Molecular Weight

586.38

References & Citations

[1]Szabo, et al. "Synthesis of α‐Hydroxy‐1, 2, 3‐Triazole‐linked Sialyltransferase Inhibitors and Evaluation of Selectivity Towards ST3GAL1, ST6GAL1 and ST8SIA2." ChemMedChem 19.16 (2024) : e202400088.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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