ST-162

• Description:

  ST-162 is a MAPK/PI3K dual antagonist. ST-162 exhibits antitumor activity and can increase the efficacy of immune checkpoint blockers. ST-162 can be used for the research of cancer, such as melanoma[1].

• UNSPSC:

  12352005

• Target:

  P38 MAPK; PI3K

• Related Pathways:

  MAPK/ERK Pathway; PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Smiles:

  O=C(NOCCOCCOCCOCCN1CCN(C2=NC(N3C4=CC=CC=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)CC1)C6=CC=C(F)C(F)=C6NC7=CC=C(I)C=C7F

• Molecular Formula:

  C40H44F5IN10O6

• Molecular Weight:

  982.74

• References & Citations:

  [1]Galbán S, et al. A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis. Mol Cancer Ther. 2017 Nov;16 (11) :2340-2350.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1883817-83-1