PSMA-1007

• Description:

  PSMA-1007 is a prostate-specific membrane antigen (PSMA) ligand. 18F-labeled PSMA-1007 can be used as a PET tracer for prostate cancer imaging. PSMA-1007 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) [1].

• UNSPSC:

  12352209

• Target:

  PSMA; Radionuclide-Drug Conjugates (RDCs)

• Type:

  Peptides

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/psma-1007.html

• Purity:

  99.35

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OC(CC[C@H](NC([C@@H](NC(C1=CC=C([N+](C)(C)C)N=C1)=O)CCC(O)=O)=O)C(NCC2=CC=C(C(N[C@@H](CC3=CC=C(C=CC=C4)C4=C3)C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)C=C2)=O)=O.[O-]C(C(F)(F)F)=O

• Molecular Formula:

  C54H64F3N9O18

• Molecular Weight:

  1184.13

• References & Citations:

  [1]Mamlins E, et al. PSMA-1007 Uptake in Ganglia of the Sympathetic Trunk and Its Intra-individual Reproducibility. Mol Imaging Biol. 2023 Jun;25 (3) :554-559. |[2]Kim SB, et al. Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [18F]PSMA-1007, in a Subcutaneous Prostate Cancer Xenograft Mouse Model. Mol Pharm. 2023 Feb 6;20 (2) :1050-1060.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  Phase 3

• CAS Number:

  [2226894-58-0]