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KSP-1007

CAT: 0804-HY-171112Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-171112Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KSP-1007 is a bicyclic boronate-based broad-spectrum β-lactamase inhibitor. KSP-1007 can effectively inhibit class A, B, C and D β-lactamases, including serine-type, metallo-type (such as NDM, VIM, IMP) and Acinetobacter baumannii OXA-type enzymes. KSP-1007 can enhance the antibacterial activity of Meropenem , reduce its MIC value, and be effective against carbapenemase-producing Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa. KSP-1007 can be used for the research of bacterial infection[1].
CAS Number
2380240-20-8
UNSPSC
12352005
Target
Bacterial; Beta-lactamase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC(C1=C2C(CCB(O2)O)=CC=C1OC3CN(C3)C([C@@H](C4=CN=CN4)N)=O)=O
Molecular Formula
C17H19BN4O6
Molecular Weight
386.17
References & Citations
[1]Takemoto K, et al. In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-β-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria. Antimicrob Agents Chemother. 2024 Jun 5;68 (6) :e0160223.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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