HDAC6-IN-50

HDAC6-IN-50

• CAS Number: 3060094-56-3
• UNSPSC Description: HDAC6-IN-50 (Compound 4) is a potent HDAC6 inhibitor with an IC50 of 35 nM. HDAC6-IN-50 can be used for the study of Parkinson's disease (PD) and Alzheimer's disease (AD) research[1].
• Target Antigen: HDAC
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hdac6-in-50.html
• Smiles: O=S(N1C2=CC=C(C=C2C=C1)OCCCN3CCN(CC3)CC#C)(C4=CC=C(C=C4)C(NO)=O)=O
• Molecular Weight: 496.58
• References & Citations: [1]Mireia Toledano-Pinedo, et al. Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases. J Med Chem. 2024 Sep 26;67(18):16533-16555.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported