HDAC6-IN-23

• Description:

  HDAC6-IN-23 (compound 9) is an orally active HDAC6 inhibitor[1].

• UNSPSC:

  12352005

• Target:

  HDAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hdac6-in-23.html

• Purity:

  99.61

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  FC(F)C(O1)=NN=C1C(C=N2)=CC=C2CN3N=NC(C4=NC=CC=C4)=N3

• Molecular Formula:

  C15H10F2N8O

• Molecular Weight:

  356.29

• References & Citations:

  [1]Ripa L, et al. Selective and Bioavailable HDAC6 2- (Difluoromethyl) -1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism [published online ahead of print, 2023 Oct 5]. J Med Chem. 2023;10.1021/acs.jmedchem.3c01269.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2991427-09-7]