Tyk2-IN-8

• UNSPSC Description:

  Tyk2-IN-8 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].

• Target Antigen:

  Isotope-Labeled Compounds; JAK

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Epigenetics;JAK/STAT Signaling;Others;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Solubility:

  DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  [2H]C([2H])([2H])OC1=C(C2=NN(C)C=N2)C=CC=C1NC3=C(N=NC(NC(C4CC4)=O)=C3)C(NC)=O

• Molecular Weight:

  425.46

• References & Citations:

  [1]Xiangyang Chen, et al. Heterocyclic compounds for inhibiting tyk2 activities. WO2021180072A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2704587-24-4