PPACK II (diTFA)

PPACK II (diTFA)

• CAS Number: 649748-23-2
• UNSPSC Description: PPACK II diTFA is an irreversible and specific glandular and plasma kallikreins inhibitor[1].
• Target Antigen: Kallikrein
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/ppack-ii-ditfa.html
• Purity: 95.04
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O
• Molecular Weight: 729.07
• References & Citations: [1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106(4):440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340(1-2):163-72.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported