PPACK

• UNSPSC Description:

  PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].

• Target Antigen:

  PAI-1

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ppack.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(CCl)=O)=O)[C@@H](CC2=CC=CC=C2)N

• Molecular Weight:

  450.96

• References & Citations:

  [1]Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  71142-71-7