PPACK II

PPACK II

• CAS Number: 74392-49-7
• UNSPSC Description: PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].
• Target Antigen: Kallikrein
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/ppack-ii.html
• Solubility: 10 mM in DMSO
• Smiles: N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O
• Molecular Weight: 501.02
• References & Citations: [1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106(4):440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340(1-2):163-72.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported