PPACK II

• Description :

  PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].

• CAS Number :

  [74392-49-7]

• UNSPSC :

  12352005

• Target :

  Kallikrein

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/ppack-ii.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O

• Molecular Formula :

  C25H33ClN6O3

• Molecular Weight :

  501.02

• References & Citations :

  [1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106 (4) :440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340 (1-2) :163-72.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported