IKKβ-IN-3

• UNSPSC Description:

  IKKβ-IN-3 (Compound hit4) is a IKKβ inhibitor with an IC50 value of 30.4 nM. IKKβ is a key enzyme in the NF-κB signaling pathway and is involved in the development of many diseases. IKKβ-IN-3 can be used in the study of CAF-induced arthritis[1].

• Target Antigen:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ikkβ-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C[C@H](NC(C[C@H](CC(CC1=CC=CC=C1)=O)O)=O)CO)C

• Molecular Weight:

  321.41

• References & Citations:

  [1]Li L, et al. The discovery of a novel IκB kinase β inhibitor based on pharmacophore modeling, virtual screening and biological evaluation. Future Med Chem. 2024;16(6):531-544.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported