IKKβ-IN-3

CAT: 0804-HY-163412Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-163412Size:1 Each

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Description

IKKβ-IN-3 (Compound hit4) is a IKKβ inhibitor with an IC50 value of 30.4 nM. IKKβ is a key enzyme in the NF-κB signaling pathway and is involved in the development of many diseases. IKKβ-IN-3 can be used in the study of CAF-induced arthritis[1].

UNSPSC

12352005

Target

IKK

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ikkβ-in-3.html

Solubility

10 mM in DMSO

Smiles

CC(C[C@H](NC(C[C@H](CC(CC1=CC=CC=C1)=O)O)=O)CO)C

Molecular Formula

C18H27NO4

Molecular Weight

321.41

References & Citations

[1]Li L, et al. The discovery of a novel IκB kinase β inhibitor based on pharmacophore modeling, virtual screening and biological evaluation. Future Med Chem. 2024;16 (6) :531-544.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IKK-β

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GTR19188912	IKK-IN-3
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sc-8032 PE	IKKγ (B-3) PE
sc-8032 AC	IKKγ (B-3) AC
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IKKβ-IN-3

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