Hydromethylthionine (dihydrobromide)

• UNSPSC Description:

  Hydromethylthionine dihydrobromide (Leukomethylene blue dihydrobromide) is a potent inhibitor of TAU protein aggregation. Hydromethylthionine dihydrobromide reduces neurodegeneration by interacting with TAU proteins and preventing them from forming neurotoxic aggregates. Hydromethylthionine dihydrobromide can be used in the study of Alzheimer's disease and other TAU related disorders[1].

• Target Antigen:

  Tau Protein

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hydromethylthionine-dihydrobromide.html

• Smiles:

  CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1.Br.Br

• Molecular Weight:

  447.23

• References & Citations:

  [1]Kondak C, et al. Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine[J]. Journal of neurochemistry, 2022, 160(2): 172-184.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 3

• CAS Number:

  951131-15-0