Products for Research Use Only
RegisterLogin

Urapidil (hydrochloride)

CAT: 0804-HY-B0354A-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0354A-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist with a pIC50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect[1][2].
CAS Number
64887-14-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor; Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/urapidil-hydrochloride.html
Purity
99.97
Solubility
DMSO : 14.29 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C)C(C=C(NCCCN2CCN(C3=CC=CC=C3OC)CC2)N1C)=O.Cl
Molecular Formula
C20H30ClN5O3
Molecular Weight
423.94
Precautions
H302, H315, H319, H335
References & Citations
[1]Gross, G., G. Hanft, and N. Kolassa, Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for alpha 1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch Pharmacol, 1987. 336 (6) : p. 597-601.|[2]Buch, J., Urapidil, a dual-acting antihypertensive agent: Current usage considerations. Adv Ther, 2010. 27 (7) : p. 426-43.|[3]Vanhaesebrouck S, et al. Neonatal transient respiratory depression after maternal urapidil infusion for hypertension. Eur J Pediatr. 2009 Feb;168 (2) :221-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor; mLAG-3; α adrenergic receptor

Related Products

CatalogName
HY-B0716-01Urapidil
HY-B0716S2Urapidil-d4
HY-B0716RUrapidil (Standard)
HY-B0716S1Urapidil-d3
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)

Alternative Products

CatalogName
TRC-U815400-100MGUrapidil Hydrochloride
TRC-U815402-100MGUrapidil-d4 Hydrochloride
A11704-100Urapidil hydrochloride 100mg
A11704-1000Urapidil hydrochloride 1g
A11704-500Urapidil hydrochloride 500mg
A11704-200Urapidil hydrochloride 200mg
A11704-50Urapidil hydrochloride 50mg
A11704-10mM-DUrapidil hydrochloride 10mM * 1mL in DMSO
BA5049-5.1Urapidil

Popular Products