Urapidil

• Description:

  Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  5-HT Receptor; Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Urapidil.html

• Concentration:

  10mM

• Purity:

  99.30

• Solubility:

  DMSO : 25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles:

  O=C1N(C)C(C=C(NCCCN2CCN(C3=CC=CC=C3OC)CC2)N1C)=O

• Molecular Formula:

  C20H29N5O3

• Molecular Weight:

  387.48

• Precautions:

  H302

• References & Citations:

  [1]Bopp C, et al. The effect of urapidil, an alpha-1 adrenoceptor antagonist and a 5-HT1A agonist, on the vascular tone of the porcine coronary and pulmonary arteries, the rat aorta and the human pulmonary artery. Eur J Pharmacol. 2016 May 15;779:53-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  5-HT1 Receptor; mLAG-3

• CAS Number:

  [34661-75-1]