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LN6023 (hydrochloride)

CAT: 0804-HY-172541Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172541Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LN6023 (hydrochloride) (Compound 27) is a CXCR7 agonist. LN6023 (hydrochloride) induces the recruitment of β-arrestin in HEK293T cells expressing human CXCR7 (EC50 = 3.5 µM) . LN6023 (hydrochloride) reduces the surface level of P-selectin in isolated and washed human platelets. LN6023 (hydrochloride) can be used to study platelet-mediated thrombosis[1].
UNSPSC
12352005
Target
CXCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C1C=C(N=C2N1N=C(S2)NCCCN3CCC(CC3)C(NC(C)(C)C)=O)CC.Cl.Cl
Molecular Formula
C20H34Cl2N6O2S
Molecular Weight
493.49
References & Citations
[1]Bayrak A, et al. Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. J Med Chem. 2022 Oct 13;65 (19) :13365-13384.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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