Urapidil-d4

Urapidil-d4

• CAS Number: 1795122-12-1
• UNSPSC Description: Urapidil-d4 is the deuterium labeled Urapidil[1]. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist[2].
• Target Antigen: 5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology
• Solubility: DMSO : 25 mg/mL (ultrasonic;warming)
• Smiles: COC1=C(N2CC([2H])([2H])N(C([2H])([2H])C2)CCCNC(N(C(N3C)=O)C)=CC3=O)C=CC=C1
• Molecular Weight: 391.50
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Bopp C, et al. The effect of urapidil, an alpha-1 adrenoceptor antagonist and a 5-HT1A agonist, on the vascular tone of the porcine coronary and pulmonary arteries, the rat aorta and the human pulmonary artery. Eur J Pharmacol. 2016 May 15;779:53-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported