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Urapidil-d3

CAT: 0804-HY-B0716S1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0716S1Size:1 mg
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Description
Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.
CAS Number
[1398066-08-4]
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease; Endocrinology
Purity
99.93
Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
Smiles
[2H]C([2H])([2H])OC1=C(N2CCN(CC2)CCCNC(N(C(N3C)=O)C)=CC3=O)C=CC=C1
Molecular Formula
C20H26D3N5O3
Molecular Weight
390.49
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bopp C, et al. The effect of urapidil, an alpha-1 adrenoceptor antagonist and a 5-HT1A agonist, on the vascular tone of the porcine coronary and pulmonary arteries, the rat aorta and the human pulmonary artery. Eur J Pharmacol. 2016 May 15;779:53-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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