Urapidil-d3

• Description:

  Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

• UNSPSC:

  12352005

• Target:

  5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling; Others

• Field of Research:

  Neurological Disease; Endocrinology

• Purity:

  99.93

• Solubility:

  DMSO : 25 mg/mL (ultrasonic; warming)

• Smiles:

  [2H]C([2H])([2H])OC1=C(N2CCN(CC2)CCCNC(N(C(N3C)=O)C)=CC3=O)C=CC=C1

• Molecular Formula:

  C20H26D3N5O3

• Molecular Weight:

  390.49

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bopp C, et al. The effect of urapidil, an alpha-1 adrenoceptor antagonist and a 5-HT1A agonist, on the vascular tone of the porcine coronary and pulmonary arteries, the rat aorta and the human pulmonary artery. Eur J Pharmacol. 2016 May 15;779:53-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• Isoform:

  5-HT1 Receptor

• CAS Number:

  1398066-08-4