ACT-678689

• Description :

  ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].

• CAS Number :

  [1783256-96-1]

• UNSPSC :

  12352005

• Target :

  Tryptophan Hydroxylase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/act-678689.html

• Purity :

  99.91

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  CS(=O)(NC1=NC(Cl)=C(OCC(N2CCC3=C(N4C(SC(C)=N4)=N3)[C@@H]2C5=CC=C(C)C=C5F)=O)C=C1)=O

• Molecular Formula :

  C23H22ClFN6O4S2

• Molecular Weight :

  565.04

• References & Citations :

  [1]Daniel Bur, et al. Tricyclic piperidine compounds. WO2015075023A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported