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SR 142948A

CAT: 0804-HY-124767-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124767-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR 142948A is a non-peptide neuropeptide neuropeptin (NT) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system[1].
CAS Number
184162-21-8
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr-142948a.html
Purity
99.0
Solubility
H2O : 10 mg/mL (ultrasonic;warming)
Smiles
O=C(C1(NC(C2=NN(C3=CC=C(C(N(CCCN(C)C)C)=O)C=C3C(C)C)C(C4=C(OC)C=CC=C4OC)=C2)=O)C5CC6CC(C5)CC1C6)O.Cl
Molecular Formula
C39H52ClN5O6
Molecular Weight
722.31
References & Citations
[1]Leonetti M, et al. The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, 365: 427-433.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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