SR 142948A

• UNSPSC Description:

  SR 142948A is a non-peptide neuropeptide neuropeptin (NT) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sr-142948a.html

• Purity:

  98.90

• Solubility:

  H2O : 10 mg/mL (ultrasonic;warming)

• Smiles:

  O=C(C1(NC(C2=NN(C3=CC=C(C(N(CCCN(C)C)C)=O)C=C3C(C)C)C(C4=C(OC)C=CC=C4OC)=C2)=O)C5CC6CC(C5)CC1C6)O.Cl

• Molecular Weight:

  722.31

• References & Citations:

  [1]Leonetti M, et al. The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, 365: 427-433.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  184162-21-8