CC-90001

CAT: 0804-HY-138304-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-138304-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK) . CC-90001 shows 12.9-fold selectivity for JNK1 over JNK2 in a cell-based model. CC-90001 can be used for the research of idiopathic pulmonary fibrosis[1][2].

CAS Number

1403859-14-2

UNSPSC

12352005

Target

JNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cc-90001.html

Concentration

10mM

Purity

99.75

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CN=C(NC(C)(C)C)N=C1N[C@H]2C[C@@H](O)[C@H](C)CC2)N

Molecular Formula

C16H27N5O2

Molecular Weight

321.42

References & Citations

[1]Bennett B, et, al. CC-90001, a Second Generation Jun N-Terminal Kinase (JNK) Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine 2017; 195:A5409.|[2]Kolb M, et, al. Therapeutic targets in idiopathic pulmonary fibrosis. Respir Med. 2017 Oct;131:49-57.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

JNK1; JNK2

Related Products

Catalog	Name
HY-P991346	CC-90006
HY-132304-01	CC-90005
HY-P99172-01	CC-90002
HY-112570-01	CC-90003
HY-P10534	Ccβ
HY-101488-01	CC-885
HY-16962-01	CC-115
HY-E70880A	Endoglycosidase CC
HY-108709-01	CC-671
HY-179457	CC-11

Alternative Products

Catalog	Name
BA6460-25	CC-90001
GTR19063678-01	Ccβ
BA4961-1	CC-90005
BA3793-50	CC-671
B6114-5	CC-115
B6171-25	CC-223

CC-90001

Related Products

Alternative Products

Popular Products