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AS2034178 (free base)

CAT: 0804-HY-P1124Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1124Size:1 Each
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Description
AS2034178 free base, a specific and orally active GPR40 agonist, exhibits glucose-dependent insulin secretion enhancement. AS2034178 free base has potential for type 2 diabetes mellitus research[1].
CAS Number
1030846-42-4
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/as2034178-free-base.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC1=CC=C(NCC2=CC=CC3=C2CCCN3CCOC4=CC=CC=C4)C=C1F
Molecular Formula
C27H29FN2O3
Molecular Weight
448.53
References & Citations
[1]Tanaka H, et al. Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion. J Pharmacol Exp Ther. 2013;346 (3) :443-452.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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