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Choline (bitartrate)

CAT: 0804-HY-101036-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101036-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2]. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism[3].
CAS Number
87-67-2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; mAChR
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/choline-bitartrate.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 55 mg/mL (ultrasonic) |H2O : 120 mg/mL (ultrasonic)
Smiles
OCC[N+](C)(C)C.O=C(O)[C@H](O)[C@@H](O)C([O-])=O
Molecular Formula
C9H19NO7
Molecular Weight
253.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Hollenbeck CB, et al. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012 Jun;12 (2) :100-13.|[2]Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28 (2) :159-65.|[3]Shinobu Kuwae, et al. Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines with optimized choline content. Cytotechnology. 2018 Jun;70 (3) :939-948.|[4]Rebecca C Schugar, et al. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet. PLoS One. 2013 Aug 29;8 (8) :e74806.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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