Norepinephrine (bitartrate monohydrate)

• UNSPSC Description:

  Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4].

• Target Antigen:

  Adrenergic Receptor; Autophagy; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Autophagy;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease; Endocrinology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Norepinephrine-bitartrate-monohydrate.html

• Smiles:

  OC1=CC=C([C@@H](O)CN)C=C1O.O=C(O)[C@H](O)[C@@H](O)C(O)=O.O

• Molecular Weight:

  337.28

• References & Citations:

  [1]MacGregor DA, et al. Relative efficacy and potency of beta-adrenoceptor agonists for generating cAMP in human lymphocytes. Chest. 1996 Jan;109(1):194-200.|[2]Littlejohn NK, et al. Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. Cell Rep. 2016 Aug 9;16(6):1548-60.|[3]Brian P Ramos, et al. Adrenergic pharmacology and cognition: focus on the prefrontal cortex. Pharmacol Ther. 2007 Mar;113(3):523-36.|[4]Xinyu Xu, et al. Binding pathway determines norepinephrine selectivity for the human β 1 AR over β 2 AR. Cell Res. 2021 May;31(5):569-579.Br J Pharmacol. 2020 Aug;177(15):3389-3402. |Cell Rep. 2019 Dec 3;29(10):2936-2943.e4. |J Nutr Biochem. 2018 May 1;58:110-118.|Leiden University. Institute of Biology Leiden (IBL) , Faculty of Science.|Nature. 2024 Dec 18.|Neuroscience. 2019 Mar 1;401:59-72. |Research Square Preprint. 2021 Aug.|Theranostics. 2022 Jun 6;12(10):4718-4733.|ACS Nano. 2022 Aug 23;16(8):12553-12568.|Biochem Biophys Res Commun. 2023 Mar 24;657:108-118.|bioRxiv. 2023 Oct 13.|bioRxiv. 2024 July 31.|bioRxiv. 2024 November 03.|Cell Commun Signal. 2024 Jul 25;22(1):375.|Cell Death Dis. 2020 Aug 18;11(8):644.|Cell Mol Immunol. 2023 Jan 5.|Cell Rep Med. 2023 May 24;101061.|Eur J Pharmacol. 2022 May 12;175022.|Food Science and Human Wellness. 2023 Nov;12(6);2061-2072.|Gene. 2023 Aug 31;147753.|Int J Mol Sci. 2022, 23(20), 12420.|J Am Heart Assoc. 2019 Jan 8;8(1):e009871.|J Biol Chem. 2024 Oct 23:107924.|J Cancer. 2024 Sep 9;15(17):5691-5709.|J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:220-227.|J Ethnopharmacol. 2024 Sep 26:118860.|J Therm Biol. 2024 Jul 2:123:103906.|Nat Commun. 2022 Jul 25;13(1):4278.|Nat Commun. 2024 May 7;15(1):3834.|Neurochem Int. 2020 Dec 16;104942.|Sci Rep. 2022 Jun 15;12(1):9936.|SSRN. 2023 May 8.|Cardiovasc Res. 2018 Feb 1;114(2):300-311. |Cell Biochem Funct. 2024 Jan 11.|FASEB J. 2020 Nov;34(11):14892-14904.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  108341-18-0