Glycerophosphoinositol (choline)

• UNSPSC Description:

  Glycerophosphoinositol choline is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2].

• Target Antigen:

  Endogenous Metabolite; nAChR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/glycerophosphoinositol-choline.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[N+](C)(C)CCO.OC[C@@H](O)COP(O[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)O)O)([O-])=O

• Molecular Weight:

  437.38

• References & Citations:

  [1] M Q Holmes-McNary, et al. Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res. 1997 Jul 18;101(1-2):9-16.|[2] T J Rowley, et al. Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain. Br J Anaesth. 2010 Aug;105(2):201-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  425642-32-6