Products for Research Use Only

Dactolisib Tosylate

CAT: 1568-C03577-5mgSize: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C03577-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1028385-32-1
Synonyms
BEZ235 Tosylate, NVP-BEZ 235 Tosylate
Target
PI3K
Applications
PI3K/Akt/mTOR
Molecular Formula
C30H23N5O.C7H8O3S
Additionnal Information
Dactolisib Tosylate (BEZ235 Tosylate, NVP-BEZ 235 Tosylate) is an imidazo[4,5-c]quinoline derivative and dual inhibitor of PI3K/mTOR with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It blocks mTORC1/mTORC2 and demonstrates potent antitumor activity in experimental cancer models.