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Dactolisib (Tosylate) (Standard)

CAT: 0804-HY-15174R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15174R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dactolisib (Tosylate) (Standard) is the analytical standard of Dactolisib (Tosylate) . This product is intended for research and analytical applications. Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
CAS Number
1028385-32-1
UNSPSC
12352100
Hazard Statement
H302, H312, H332
Target
Autophagy; mTOR; PI3K; Reference Standards
Related Pathways
Autophagy; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Purity
98.95
Smiles
CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O.CC7=CC=C(S(=O)(O)=O)C=C7
Molecular Formula
C37H31N5O4S
Molecular Weight
641.74
Precautions
H302, H312, H332
References & Citations
[1]Maira SM, et al. Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther, 2008, 7 (7), 1851-1863.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported

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Alternative Products

CatalogName
T14552-01Dactolisib Tosylate
A11327-500Dactolisib Tosylate 500mg
A11327-50Dactolisib Tosylate 50mg
A11327-25Dactolisib Tosylate 25mg
A11327-200Dactolisib Tosylate 200mg
A11327-100Dactolisib Tosylate 100mg
A11327-10mM-DDactolisib Tosylate 10mM * 1mL in DMSO
T2235-01Dactolisib
C16055-200mgDactolisib (BEZ235)
GTR19240948-01Dactolisib hydrochloride

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