Dactolisib Tosylate

CAT: 0931-T14552-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T14552-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1028385-32-1
Target
MTOR|||Autophagy|||PI3K
Related Pathways
Autophagy|||PI3K/Akt/mTOR signaling
Purity
0.9991
Bioactivity
Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor targeting PI3K and mTOR, with IC50 values of 4, 75, 7, and 5 nM for PI3K?, ?, ?, and ?, respectively. It also inhibits mTORC1 and mTORC2.
Smiles
Cc1ccc(cc1)S(O)(=O)=O.Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1
Molecular Formula
C37H31N5O4S
Molecular Weight
641.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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