Dactolisib Tosylate

• Target:

  MTOR|||Autophagy|||PI3K

• Related Pathways:

  Autophagy|||PI3K/Akt/mTOR signaling

• Purity:

  0.9991

• Bioactivity:

  Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor targeting PI3K and mTOR, with IC50 values of 4, 75, 7, and 5 nM for PI3K?, ?, ?, and ?, respectively. It also inhibits mTORC1 and mTORC2.

• Smiles:

  Cc1ccc(cc1)S(O)(=O)=O.Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1

• Molecular Formula:

  C37H31N5O4S

• Molecular Weight:

  641.74

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1028385-32-1