ADX-10061

• Description :

  ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia[1].

• Product Name Alternative :

  CEE 03-310; NNC 687

• UNSPSC :

  12352005

• Target :

  Adenylate Cyclase; Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/adx-10061.html

• Smiles :

  OC1=C([N+]([O-])=O)C=C2CCN(C)C[C@H](C3=C(OCC4)C4=CC=C3)C2=C1

• Molecular Formula :

  C19H20N2O4

• Molecular Weight :

  340.37

• References & Citations :

  [1]Andersen PH, et al. NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists. Eur J Pharmacol. 1992;219 (1) :45-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  D1 Receptor; D2 Receptor

• CAS Number :

  [128022-68-4]