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NFF-3 (TFA)

CAT: 0804-HY-P2185A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2185A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity[1].
UNSPSC
12352209
Target
MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nff-3-tfa.html
Purity
98.54
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
O=[N+]([O-])C(C=C(C=C1)[N+]([O-])=O)=C1NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCC)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@H](CCCCN)NC([C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC(CC(C4=CC=C(OC)C=C4O5)=CC5=O)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C80H111F3N22O22
Molecular Weight
1789.87
References & Citations
[1]Giricz O, et al. Comparison of metalloproteinase protein and activity profiling. Anal Biochem. 2011 Feb 1;409 (1) :37-45.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MMP-10; MMP-3

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