Phrixotoxin 3 TFA

CAT: 0931-MF-0155576-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0155576-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Phrixotoxin 3 TFA is a potent inhibitor of voltage-gated sodium channels, with IC50 values of 0.6 nM for NaV1.2, 42 nM for NaV1.3, 72 nM for NaV1.4, 288 nM for NaV1.1, and 610 nM for NaV1.5. This compound modulates the activity of these channels similarly to traditional gating-modifier toxins, inducing a depolarizing shift in gating kinetics and obstructing the inward sodium current.
Molecular Formula
C178H270F3N51O50S6
Molecular Weight
4173.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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PHX002-50010Phrixotoxin-2
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