Products for Research Use Only
RegisterLogin

Histatin-3 (TFA)

CAT: 0804-HY-P5272-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P5272-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN) . Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM[1].
CAS Number
112844-49-2
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/histatin-3.html
Purity
99.37
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)CC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CC(O)=O)=O)CC1=CC=C(O)C=C1)=O)CC(C)C)=O)CC2=CC=C(O)C=C2)=O)CC(N)=O)=O)CO)=O)CCCNC(N)=N)=O)CC3=CC=C(O)C=C3)=O)=O)CCCNC(N)=N)=O)CC4=CNC=N4)=O)CO)=O)CC5=CNC=N5)=O)CC6=CNC=N6)=O)CCCCN)=O)CCC(O)=O)=O)CC7=CNC=N7)=O)CC8=CC=CC=C8)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCCN)=O)CC9=CC=C(O)C=C9)=O)=O)CC%10=CNC=N%10)=O)CC%11=CNC=N%11)=O)CCCNC(N)=N)=O)CCCCN)=O)C)=O)CC%12=CNC=N%12)=O)CO.O=C(C(F)(F)F)O.[x]
Molecular Formula
C178H258N64O48.xC2HF3O2
Molecular Weight
4062.35 (free acid)
Precautions
H302, H315, H319, H335
References & Citations
[1]A Basak, et al. Histidine-rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1. J Pept Res. 1997 Jun;49 (6) :596-603.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P0273A-01Histatin 5 (TFA)
HY-P70298-01Histatin-3/HTN3, Human
HY-P2365Histatin-8
HY-P0273Histatin 5
HY-P1218APhrixotoxin 3 (TFA)
HY-P3320APhytochelatin 3 (TFA)
HY-P2185A-01NFF-3 (TFA)
HY-P2358APSMα3 (TFA)
HY-144302AAAK1-IN-3 (TFA)
HY-P2166A-01MMP3 inhibitor 3 (TFA)

Alternative Products

CatalogName
T83715-01Histatin 3 TFA
MBS3847773-01Histatin-3 TFA
A23193-1Histatin-3 TFA 1mg
A23193-10Histatin-3 TFA 10mg
A23193-5Histatin-3 TFA 5mg
T75755-01Histatin 5 TFA
M30145Histatin 5 (TFA)
T83689-01Histatin 8 TFA
MBS3612750-01Histatin 5(TFA)(115966-68-2,free)
GTR19029596-01Histatin 5 (TFA) (115966-68-2, free)

Popular Products