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PCSK9-IN-22

CAT: 0804-HY-160036-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160036-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PCSK9-IN-22 (compound 29) is an orally active inhibitor of PCSK9. PCSK9-IN-22 inhibits the interaction of the protein with LDLR in vivo[1].
CAS Number
2794203-47-5
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-in-22.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CCC1)CN1CC2=CC(NC(C3=CC(C4=CC=CC=C4)=CC=N3)=O)=CC(N5C=NC(C)=C5)=C2
Molecular Formula
C28H30N6O
Molecular Weight
466.58
References & Citations
[1]Phillip Albert Coghlan, et al. Heterocyclic inhibitors of pcsk9. WO2022133529A1. 2022-06-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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