KK-103

• UNSPSC Description:

  KK-103 is a precursor of leucine-enkephalin (Leu-ENK) overcomes high proteolytic instability of Leu-ENK via markedly increased plasma stability in mice that has antinociceptive effect[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/kk-103.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)C[C@@H](C(O)=O)NC([C@@H](NC(CNC(CNC([C@@H](NC(C(C)(C)C)=O)CC1=CC=C(C=C1)O)=O)=O)=O)CC2=CC=CC=C2)=O

• Molecular Weight:

  639.74

• References & Citations:

  [1]Lukas Hohenwarter, et al. A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects. Mol Pharm. 2024 Jan 20.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2775287-98-2