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KK-103

CAT: 0804-HY-P6053Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P6053Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KK-103 is a precursor of leucine-enkephalin (Leu-ENK) overcomes high proteolytic instability of Leu-ENK via markedly increased plasma stability in mice that has antinociceptive effect[1].
CAS Number
2775287-98-2
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kk-103.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@@H](NC(CNC(CNC([C@@H](NC(C(C)(C)C)=O)CC1=CC=C(C=C1)O)=O)=O)=O)CC2=CC=CC=C2)=O
Molecular Formula
C33H45N5O8
Molecular Weight
639.74
References & Citations
[1]Lukas Hohenwarter, et al. A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects. Mol Pharm. 2024 Jan 20.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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