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KK-92A

CAT: 0804-HY-159624Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159624Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KK-92A, a blood-brain barrier penetrated GABAB positive allosteric modulator (PAM), suppresses alcohol self-administration and cue-induced reinstatement of alcohol seeking in rats[1].
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kk-92a.html
Smiles
OCC1=NC=C(C2=CC=C(C=C2)C(F)(F)F)C(NC3CCCCCC3)=N1
Molecular Formula
C19H22F3N3O
Molecular Weight
365.39
References & Citations
[1]Paola Maccioni, et al. The Novel Positive Allosteric Modulator of the GABAB Receptor, KK-92A, Suppresses Alcohol Self-Administration and Cue-Induced Reinstatement of Alcohol Seeking in Rats. Front Cell Dev Biol. 2021 Oct 28:9:727576.|[2]Xia Li, et al. KK-92A, a novel GABAB receptor positive allosteric modulator, attenuates nicotine self-administration and cue-induced nicotine seeking in rats. Psychopharmacology (Berl) . 2017 May;234 (9-10) :1633-1644.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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