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EU-103

CAT: 0804-HY-P991217Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P991217Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EU-103 is a humanized monoclonal antibody targeting V-Set And Immunoglobulin Domain Containing 4 (VSIG4) with a KD value ranging from 10−7 and 10−9. EU-103 blocks the interaction between VSIG4 and CD8+ T cells, promotes the conversion of M2 macrophages into M1 macrophages, induces the proliferation of CD8+ T cells and the secretion of pro-inflammatory cytokines, thereby inhibiting tumor growth. EU-103 is promising for research of cancers, such as bladder cancer, breast cancer, and colon cancer[1].
UNSPSC
12352203
Target
Transmembrane Glycoprotein
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[EU-103]
References & Citations
[1]Byoung S. Kwon, et al. Anti-human vsig4 antibodies and uses thereof. WO2020069507A1. 2020-04-02.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

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