Rb (AB2272) Rabbit mAb

CAT: 0808-M3561-01Size: 20 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0808-M3561-01Size:20 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Synonyms

RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Gene Name

RB1

Gene ID

5925

Swiss Prot

P06400

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB; IF; IP; ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of Retinoblastoma-associated protein protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

Retinoblastoma-associated protein

Related Products

Catalog	Name
M3667-01	FAM111A (AB2252) Rabbit mAb
M3581-01	MFN1 (AB2282) Rabbit mAb
M3562-01	Smad3 (AB2273) Rabbit mAb
M3477-01	RSK2 (AB2270) Rabbit mAb
M3677-01	SGSH (AB2262) Rabbit mAb
M3647-01	RAVER2 (AB2232) Rabbit mAb
M3642-01	DPEP3 (AB2227) Rabbit mAb
M3577-01	VCAM1 (AB2278) Rabbit mAb
M3657-01	PACSIN3 (AB2242) Rabbit mAb
M3578-01	ATM (AB2279) Rabbit mAb

Alternative Products

Catalog	Name
RTR015	Rabbit-to-Rabbit Blocking Reagent
ES20751-01	Gab1 Rabbit rabbit pAb
ES20703-01	JAK2 Rabbit rabbit pAb
ES20758-01	ERK1 Rabbit rabbit pAb
ES20659-01	NBR1 Rabbit rabbit pAb
ES20825-01	ATG7 Rabbit rabbit pAb
ES20831-01	ATG13 Rabbit rabbit pAb
ES20599-01	VEGF Rabbit rabbit pAb
ES20596-01	WIPI2 Rabbit rabbit pAb
AR05252PU-N	Rabbit IgG Rabbit Protein

Rb (AB2272) Rabbit mAb

Related Products

Alternative Products

Popular Products