Gln-AMS

• UNSPSC Description:

  Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.

• Target Antigen:

  Aminoacyl-tRNA Synthetase; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Gln-AMS.html

• Purity:

  99.21

• Solubility:

  DMSO : 120 mg/mL (ultrasonic)

• Smiles:

  NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCC(N)=O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1

• Molecular Weight:

  474.45

• References & Citations:

  [1]Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.|[2]Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  209543-57-7