Asp-AMS

CAT: 0804-HY-112860-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:0804-HY-112860-01Size:5 mg

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Description

Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.

CAS Number

[828288-98-8]

UNSPSC

12352005

Target

Aminoacyl-tRNA Synthetase; Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Asp-AMS.html

Purity

98.14

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=C2N=CN([C@@H]([C@H](O)[C@@H]3O)O[C@@H]3COS(=O)(NC([C@@H](N)CC(O)=O)=O)=O)C2=NC=N1

Molecular Formula

C14H19N7O9S

Molecular Weight

461.41

References & Citations

[1]Messmer M, et al. Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs. Biochimie. 2009 May;91 (5) :596-603.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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