Asp-AMS

• Description :

  Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.

• UNSPSC :

  12352005

• Target :

  Aminoacyl-tRNA Synthetase; Mitochondrial Metabolism

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/Asp-AMS.html

• Purity :

  98.14

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  NC1=C2N=CN([C@@H]([C@H](O)[C@@H]3O)O[C@@H]3COS(=O)(NC([C@@H](N)CC(O)=O)=O)=O)C2=NC=N1

• Molecular Formula :

  C14H19N7O9S

• Molecular Weight :

  461.41

• References & Citations :

  [1]Messmer M, et al. Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs. Biochimie. 2009 May;91 (5) :596-603.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [828288-98-8]