Asp-AMS

• Description:

  Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.

• UNSPSC:

  12352005

• Target:

  Aminoacyl-tRNA Synthetase; Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Asp-AMS.html

• Purity:

  98.14

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  NC1=C2N=CN ([C@@H] ([C@H] (O) [C@@H]3O) O[C@@H]3COS (=O) (NC ([C@@H] (N) CC (O) =O) =O) =O) C2=NC=N1

• Molecular Formula:

  C14H19N7O9S

• Molecular Weight:

  461.41

• References & Citations:

  [1]Messmer M, et al. Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs. Biochimie. 2009 May;91 (5) :596-603.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  828288-98-8