MMAE-SMCC

CAT: 0804-HY-135660-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135660-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
MMAE-SMCC is a agent-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody agent conjugate.
CAS Number
[2021179-11-1]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmae-smcc.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCSC(C3)C(N(CC4CCC(C(ON5C(CCC5=O)=O)=O)CC4)C3=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C58H89N7O14S
Molecular Weight
1140.43
References & Citations
[1]Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14 (40) :9501-9518.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin

Related Products

CatalogName
HY-42360-01SMCC
HY-116063-01Doxorubicin-SMCC
HY-P2853AHemocyanin-SMCC
HY-126494-01DM4-SMCC
HY-101070-01SMCC-DM1
HY-W123007LC-SMCC
HY-171572-01Atezolizumab-MMAE
HY-171269Anetumab-MMAE
HY-171135-01Cetuximab MMAE
HY-15741-01Mc-MMAE

Alternative Products

CatalogName
MBS133215MMAE-SMCC
BA2364-5000SMCC
P0642-5mgSMCC Activated Allophycocyanin (SMCC-APC)
B2344-5MMAE
P0640-1mgSMCC Activated R-Phycoerythrin (SMCC-RPE)

Popular Products