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MMAE

CAT: 0026-B2344-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2344-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MMAE (Monomethyl auristatin E) is a synthetic derivative of dolastatin 10 that functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. Suppresses tumor cell viability in vitro (GIC50 values are 0.22, 0.49 and 0.54 nM in BT474, MDA-MB-361-DYT2 and N87 cells, respectively). It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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