QS-57

QS-57

• UNSPSC Description: QS-57 is a PROTAC targeting BRD4. QS-57 can be used as a 14-3-3 molecular glue. (Red: EN171 (HY-W1005067), black: (2-Aminoethyl) carbamic acid (HY-W398806), Blue: JQ-1 (carboxylic acid) (HY-78695))[1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/qs-57.html
• Smiles: C=CC(N1CCC2(C1)CCN(C2)CC3=CC=C(C=C3)C(NCCNC(C[C@@H]4N=C(C5=C(N6C(C)=NN=C46)SC(C)=C5C)C7=CC=C(C=C7)Cl)=O)=O)=O
• Molecular Weight: 739.33
• References & Citations: [1]Shao Q, et al. Targeted Protein Localization by Covalent 14–3–3 Recruitment[J]. Journal of the American Chemical Society, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported