QS-57

• UNSPSC Description:

  QS-57 is a PROTAC targeting BRD4. QS-57 can be used as a 14-3-3 molecular glue. (Red: EN171 (HY-W1005067), black: (2-Aminoethyl) carbamic acid (HY-W398806), Blue: JQ-1 (carboxylic acid) (HY-78695))[1].

• Target Antigen:

  PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/qs-57.html

• Smiles:

  C=CC(N1CCC2(C1)CCN(C2)CC3=CC=C(C=C3)C(NCCNC(C[C@@H]4N=C(C5=C(N6C(C)=NN=C46)SC(C)=C5C)C7=CC=C(C=C7)Cl)=O)=O)=O

• Molecular Weight:

  739.33

• References & Citations:

  [1]Shao Q, et al. Targeted Protein Localization by Covalent 14–3–3 Recruitment[J]. Journal of the American Chemical Society, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported