QS-21-Xyl

• Description :

  QS-21-Xyl is an immune system-targeted adjuvant, acting as an agonist for T-cell and B-cell immune responses. QS-21-Xyl enhances vaccine immunogenicity by activating dendritic cells and promoting antigen presentation. QS-21-Xyl is promising for research of oncology vaccines (e.g., melanoma) and infectious disease vaccines (e.g., HIV, malaria) [1].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Purity :

  97.23

• Smiles :

  O[C@H]([C@@H]([C@H]([C@@H](O1)C)O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O[C@H]3[C@@H]([C@H]([C@@H](CO3)O)O)O)O)O)[C@@H]1O[C@H]([C@H]([C@H]([C@H](O4)C)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)O[C@@H]5O[C@H]([C@@H]([C@H]5O)O)CO)=O)=O)O)[C@@H]4OC([C@]67[C@](CC(C)(CC7)C)([H])C8=CC[C@@]([C@@]9([C@@]([C@@](C)([C@H](CC9)O[C@H]%10[C@@H]([C@H]([C@@H]([C@H](O%10)C(O)=O)O)O[C@H]%11[C@@H]([C@H]([C@@H](CO%11)O)O)O)O[C@@H]%12O[C@@H]([C@@H]([C@@H]([C@H]%12O)O)O)CO)C=O)([H])CC%13)C)([H])[C@]%13(C)[C@@]8(C[C@H]6O)C)=O

• Molecular Formula :

  C92H148O46

• Molecular Weight :

  1990.13

• References & Citations :

  [1]Deng K, et al. Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew Chem Int Ed Engl. 2008;47 (34) :6395-8.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [250643-56-2]