QS-21-Xyl

• Description:

  QS-21-Xyl is an immune system-targeted adjuvant, acting as an agonist for T-cell and B-cell immune responses. QS-21-Xyl enhances vaccine immunogenicity by activating dendritic cells and promoting antigen presentation. QS-21-Xyl is promising for research of oncology vaccines (e.g., melanoma) and infectious disease vaccines (e.g., HIV, malaria) [1].

• UNSPSC:

  12352005

• Target:

  Others

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection

• Purity:

  97.23

• Smiles:

  O[C@H] ([C@@H] ([C@H] ([C@@H] (O1) C) O[C@H]2[C@@H] ([C@H] ([C@@H] (CO2) O) O[C@H]3[C@@H] ([C@H] ([C@@H] (CO3) O) O) O) O) O) [C@@H]1O[C@H] ([C@H] ([C@H] ([C@H] (O4) C) OC (C[C@@H] (O) C[C@@H] ([C@@H] (C) CC) OC (C[C@@H] (O) C[C@@H] ([C@@H] (C) CC) O[C@@H]5O[C@H] ([C@@H] ([C@H]5O) O) CO) =O) =O) O) [C@@H]4OC ([C@]67[C@] (CC (C) (CC7) C) ([H]) C8=CC[C@@] ([C@@]9 ([C@@] ([C@@] (C) ([C@H] (CC9) O[C@H]%10[C@@H] ([C@H] ([C@@H] ([C@H] (O%10) C (O) =O) O) O[C@H]%11[C@@H] ([C@H] ([C@@H] (CO%11) O) O) O) O[C@@H]%12O[C@@H] ([C@@H] ([C@@H] ([C@H]%12O) O) O) CO) C=O) ([H]) CC%13) C) ([H]) [C@]%13 (C) [C@@]8 (C[C@H]6O) C) =O

• Molecular Formula:

  C92H148O46

• Molecular Weight:

  1990.13

• References & Citations:

  [1]Deng K, et al. Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew Chem Int Ed Engl. 2008;47 (34) :6395-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  250643-56-2