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LCMV GP (61-80)

CAT: 0804-HY-P2560-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2560-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), and corresponds to amino acids 61-80. LCMV GP (61-80) is a specific epitope which can induce CD4+ T-cell response[1][2][3].
CAS Number
232598-19-5
UNSPSC
12352209
Target
Arenavirus
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lcmv-gp-61-80.html
Purity
99.80
Solubility
H2O : 0.71 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H]5N(CCC5)C(CNC([C@H](CCCCN)NC([C@H](CC(C)C)NC(CN)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C108H160N24O31
Molecular Weight
2290.60
References & Citations
[1]Rodriguez F, et, al. CD4 (+) T cells induced by a DNA vaccine: immunological consequences of epitope-specific lysosomal targeting. J Virol. 2001 Nov; 75 (21) : 10421-30.|[2]Andargachew R, et, al. CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection. J Immunol. 2018 Jul 1; 201 (1) :19-30.|[3]Homann D, et, al. Mapping and restriction of a dominant viral CD4+ T cell core epitope by both MHC class I and MHC class II. Virology. 2007 Jun 20; 363 (1) : 113-23.|[4]Hilpert C, et al. Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection. J Immunol. 2016 Oct 1;197 (7) :2780-6.|[5]Siracusa F, et al. Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow. Proc Natl Acad Sci U S A. 2018 Feb 6;115 (6) :1334-1339.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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