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DGK-IN-1

CAT: 0804-HY-135898-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135898-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DGK-IN-1 is a DGK inhibitor (DGKa/DGKz IC50: 0.65/0.25 μM) . DGK-IN-1 is a T cell activator that can be used in cancer and viral infection research[1].
CAS Number
2407892-34-4
UNSPSC
12352005
Target
DGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dgk-in-1.html
Purity
98.67
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=NC2=C(N(C)C(C=C2N3[C@@H](C)CN(C(C4=CC=C(Cl)C=C4)C5=CC=C(Cl)C=C5)[C@H](C)C3)=O)C=C1
Molecular Formula
C29H27Cl2N5O
Molecular Weight
532.46
References & Citations
[1]Velaparthi U, et al. Preparation of substituted naphthyridinone compounds useful as T cell activators. WO2020006018A1. World Intellectual Property Organization. A1 2020-01-02.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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