CD73-IN-18

• Description:

  CD73-IN-18 (compound 35j) is an orally available inhibitor of extracellular 5-nucleotidase (CD73) . CD73-IN-18 can be used in anti-cancer research[1].

• UNSPSC:

  12352005

• Target:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-18.html

• Smiles:

  O=C (C (C1=CC (NCCC2=CC=CC=C2) =C (N=N1) C3=COC=C3) =CN4) NC4=O

• Molecular Formula:

  C20H17N5O3

• Molecular Weight:

  375.38

• References & Citations:

  [1]Xu Y, et al. Discovery of Novel 5- (Pyridazin-3-yl) pyrimidine-2,4 (1H,3H) -dione Derivatives as Potent and Orally Bioavailable Inhibitors Targeting Ecto-5'-nucleotidase. J Med Chem. 2024 Oct 10.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3037968-61-6