CD73-IN-4

• Description :

  CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology[1].

• CAS Number :

  [2216764-29-1]

• UNSPSC :

  12352005

• Target :

  CD73

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cd73-in-4.html

• Concentration :

  10mM

• Purity :

  99.21

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  ClC1=NC(N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COCP(O)(O)=O)N=C3)=C3C(NC4CCCC4)=N1

• Molecular Formula :

  C16H23ClN5O7P

• Molecular Weight :

  463.81

• References & Citations :

  [1]Ehesan U Sharif , et al. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors. J Med Chem. 2021 Jan 5.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported