CD73-IN-4

• UNSPSC Description:

  CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology[1].

• Target Antigen:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-4.html

• Purity:

  99.21

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  ClC1=NC(N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COCP(O)(O)=O)N=C3)=C3C(NC4CCCC4)=N1

• Molecular Weight:

  463.81

• References & Citations:

  [1]Ehesan U Sharif , et al. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors. J Med Chem. 2021 Jan 5.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2216764-29-1