CD73-IN-21

• Description:

  CD73-IN-21 (Compound 12f) is an Ecto-5′-nucleotidase (CD73) inhibitor with Kis of 20 and 302 nM for hCD73 and mCD73, respectively. CD73-IN-21 can be used for cancers like breast cancer research[1].

• UNSPSC:

  12352005

• Target:

  CD73

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Smiles:

  O[C@@H]1[C@H](O)[C@@H](COCP([O-])(O)=O)O[C@H]1N2C=CC3=C2N=C(N=C3C4=C5C=CC=CC5=CC=C4)Cl.CC[NH+](CC)CC

• Molecular Formula:

  C28H36ClN4O7P

• Molecular Weight:

  607.03

• References & Citations:

  [1]Šímová M, et al. Identification of 6-Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5′-Nucleotidase (CD73) [J]. ACS Pharmacology & Translational Science, 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported