CD73-IN-16

• UNSPSC Description:

  CD73-IN-16 (compound 18) is an inhibitor of hCD73 with IC50 values of 0.28 μM[1].

• Target Antigen:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-16.html

• Smiles:

  ClC(C=N1)=CC2=C1NN=C2C3=CC=C4C(COC(C(O)=O)(C(O)=O)CC5=CC=CC=C5)=NNC4=C3

• Molecular Weight:

  491.88

• References & Citations:

  [1]Cunjian Shi, et al. Design, synthesis and structure-activity relationship of malonic acid non-nucleoside derivatives as potent CD73 inhibitors. Bioorg Med Chem Lett. 2024 Nov 1:112:129946.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported