α7 nAChR Modulator-2

CAT: 0804-HY-160529Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-160529Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
α7 nAChR Modulator-2 (Compound 7b) is a α7 nAChR positive allosteric modulator (PAM) with an EC50 of 2.1 μM. α7 nAChR Modulator-2 can be used for the research of cognitive disorders[1].
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α7-nachr-modulator-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)N=C(NC2=CC=C(F)C(Cl)=C2)S1)NC3=C(C)C=CC=C3C
Molecular Formula
C19H17ClFN3OS
Molecular Weight
389.87
References & Citations
[1]Yang C, et al. Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice. J Med Chem. 2024 Feb 23.|[2]Yang C, et al. Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice. J Med Chem. 2024 Feb 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products